Early Intervention The IGNITE® technique is a low morbidity, time-saving procedure. Direct hospital costs to achieve union in tibia fractures have been estimated between $7415 and $27,422 (indexed to 2002 dollars).

• Estimated cost-savings potential of over $4400
• Minimally-Invasive aspiration and injection
• Outpatient, 30-minutes OR time
• No iliac crest harvest complications and cost (estimated between $2,200 and $5,000)

“At Risk” fracture 10 weeks post-op	Percutaneous, sub-periosteal injection of IGNITE® Biocomposite	10 weeks after IGNITE® treatment
Images courtesy of Tracy Watson, MD St. Louis University Hospital St. Louis, MO

Stimulate Fracture Callus Formation

The IGNITE® Power Mix combines an injectable scaffold in demineralized bone matrix with aspirated red bone marrow. The combination provides a minimally-invasive graft with osteoconductive, osteoinductive, and osteogenic capacity. The IGNITE® Composite Graft reinforces and stimulates defect healing in poorly vascularized areas, such as the long bone diaphysis. Healing with the IGNITE® Graft proceeds via the normal stages of fracture healing.

Case Study 61 year old male
Pre-Injection A 61 year-old male with a comminuted pilon fracture sustained in a motor vehicle accident.	Post-op 2 Months After 2 months with an external fixator, definitive fixation of the tibia with a percutaneous injection of IGNITE® Power Mix Graft to fill the slow-healing fracture.	Post-op, 8 Months Two years post-op, the fracture is consolidated and the patient is ambulating pain-free.
Images courtesy of Gregory T. Altman, MD Allegheny General Hospital Pittsburgh, PA

POTENTIAL USES:

• Suspect delayed union at 6-8 weeks following index procedure with no sign of callus formation
• Delayed union with well-fixed hardware
• Fresh fractures for “High Risk” patients with one or more comorbidities such as smoking, diabetes, steroid use, etc.
• Stable (well-fixed) nonunions with no prior surgical intervention